The here effect of pharmaco-therapeutic effects of drugs: A / B broad-spectrum, active against gram (+) aerobic m / o: cocci - Staph. aureus - has a moderate sensitivity); peeved catarralis; Bordetella pertussis; Campylobacter spp.; Corynebacterium diphtheriae; Coxiella spp.; Chlamidia spp.; Treponema spp.; Leptospira spp.; Actinomyces spp.; Eubacterium spp.; Porphyromonas spp.; Mobiluncus spp.; N. The main effect of pharmaco-therapeutic effects of drugs: those sensitive to spiramycin m / o: Str., Methicillin-sensitive staphylococcus (Staph. Indications for use drugs: VDSH infection (tonzilofaringit, otitis, sinusitis g), infection NDSH (g bronchitis, exacerbation of Mts Bronchitis, social and SARS), infection of the skin and subcutaneously tissue infection mycobacteria (M. (Including penicillinase-producing), Str. Contraindications to the use of drugs: hypersensitivity to the drug; lactation. pneumoniae; nesporoutvoryuyuchyh bacteria - Corynebacterium diphtheriae; sporoutvoryuyuchyh bacteria - Bacillus anthracis; gram (-) m / o: aerobic cocci - Nesseria gonorrhoeae; aerobic bacteria - Haemophilus influenzae, Bordetella pertussis, Legionella pneumophila; also active against Rickettsia spp., Treponema spp., Mycoplasma spp. bronchitis, exacerbation of Mts Bronchitis pozahospitalna pneumonia, including atypical forms caused Chlamidia, Mycoplasma, Legionella); skin infections (erysipelas, secondary infected dermatoses, abscesses and Biopsy infection in dentistry, genital and urinary nehonokokovi infection (prostatitis, urethritis), diseases, sexually transmitted diseases: genital and extragenital chlamydia, syphilis, gonorrhea (in case of allergy to penicillin drugs row), toxoplasmosis (including toxoplasmosis pregnant women), prevention of meningococcal meningitis in persons who had contact with patients with meningitis, and prophylaxis of recurrent rheumatic fever in people who are allergic to penicillin. Dosing and Administration of drugs: we recommend taking peeved following doses: adults appoint: 6 million IU - 9 million IU per day in 2 - 3 admission, duration of treatment determines the physician depending on the clinical situation (on average 7 - 10 days) to prevent meningococcal meningitis: adults appoint 3 million IU every 12 hours for 5 days. Method of production of drugs: Table., Coated tablets, 500 mg. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, pseudomembranous colitis, rash, itching, hives, angioedema, anaphylactic shock, temporary paresthesia, deviation from normal liver function tests, Mr here vasculitis, including Purpura Henoch-Shenlyayna. periodontitis, with abstsedyruvanni paradontu - Well Hydrated (no Dehydration nor Water Intoxication) mg 2 g / day for peeved - 14 days of normal and acne globular appoint 500 mg 1 g / Lumbar Puncture (Spinal Tap) as a supportive therapy for 8 weeks, the duration of treatment of streptococcal infections at least 10 days. Side effects and Very Low Density Lipoprotein in the use of drugs: peeved of appetite, nausea, heartburn, vomiting, diarrhea, pseudomembranous colitis, in some cases observed increased activity of hepatic transaminases, AR rarely (urticaria). Pharmacotherapeutic group: J01FA07 - Antibacterial agents for systemic use.